Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 4/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | IL1B | P01584 | 1/20 | 0.51 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.51 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23766204 | 0.99 | STAT3 (0.54) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL24068471 | 0.96 | STAT3 (0.54) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL24068601 | 0.93 | STAT3 (0.54) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL25031868 | 0.92 | CRBN (0.51) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL19438825 | 0.92 | CRBN (0.55) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL19438857 | 0.92 | CRBN (0.55) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL30577345 | 0.92 | CRBN (0.55) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL20913661 | 0.92 | CRBN (0.55) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL23766134 | 0.91 | MAP1LC3B (0.51) | STAT3CRBNHDAC3HDAC1BRD4 | |
| SCHEMBL25029989 | 0.91 | STAT3 (0.54) | STAT3CRBNBRD4TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865152-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2021-08-18 | — | — | EP | disclosed |