Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.52 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | IL1B | P01584 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757061 | 0.95 | STAT3 (0.58) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL24068335 | 0.95 | STAT3 (0.58) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL24068662 | 0.95 | STAT3 (0.58) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL24068248 | 0.92 | STAT3 (0.58) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL23766029 | 0.90 | STAT3 (0.53) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL25031671 | 0.88 | STAT3 (0.56) | STAT3CRBNIKZF1CSNK1A1MAP1LC3B | |
| SCHEMBL23766204 | 0.88 | STAT3 (0.54) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL25757118 | 0.88 | CRBN (0.51) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL23766003 | 0.87 | STAT3 (0.53) | STAT3HDAC1HDAC3CRBNIKZF1 | |
| SCHEMBL25029989 | 0.87 | STAT3 (0.54) | STAT3CRBNIKZF1MAP1LC3BBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865152-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | Eubulus Biotherapeutics Inc. (CN) | 2021-08-18 | — | — | EP | disclosed |