Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A2 | P55011 | 1/20 | 0.35 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18729643 | 0.93 | SLC12A2 (0.39) | SLC12A2SLC12A5POLBGAAENPP3 | |
| SCHEMBL21565962 | 0.90 | SLC12A2 (0.37) | SLC12A2SLC12A5POLBGAAENPP3 | |
| SCHEMBL15237680 | 0.89 | SLC12A2 (0.37) | SLC12A2SLC12A5POLBGAAENPP3 | |
| SCHEMBL26837241 | 0.88 | SLC12A2 (0.36) | SLC12A2SLC12A5POLBGAAENPP3 | |
| SCHEMBL9424847 | 0.87 | PLA2G2C (0.37) | SLC12A2SLC12A5PLA2G2C | |
| SCHEMBL9424685 | 0.87 | PLA2G2C (0.37) | SLC12A2SLC12A5PLA2G2C | |
| SCHEMBL9424842 | 0.87 | PLA2G2C (0.37) | SLC12A2SLC12A5PLA2G2C | |
| SCHEMBL18029863 | 0.87 | SLC12A2 (0.35) | SLC12A2SLC12A5POLBGAAENPP3 | |
| SCHEMBL23766558 | 0.87 | SLC12A2 (0.35) | SLC12A2SLC12A5POLBGAAENPP3 | |
| SCHEMBL25382704 | 0.87 | SLC12A2 (0.37) | SLC12A2SLC12A5POLBGAAENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210253569-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | APRINOIA THERAPEUTICS INC. (CN) | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210253569-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | MAPT, APP, SLCO1B3 | SLC12A2 342/4885SLC12A5 322/4885POLB 2489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.