Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9424842 | 1.00 | PLA2G2C (0.37) | PLA2G2CSLC12A2SLC12A5FKBP1ADRD2 | |
| SCHEMBL9424685 | 1.00 | PLA2G2C (0.37) | PLA2G2CSLC12A2SLC12A5FKBP1ADRD2 | |
| SCHEMBL26837241 | 0.93 | SLC12A2 (0.36) | PLA2G2CSLC12A2SLC12A5DRD2DRD1 | |
| SCHEMBL18729643 | 0.89 | SLC12A2 (0.39) | SLC12A2SLC12A5CYP1A2CYP2D6 | |
| SCHEMBL8074534 | 0.89 | SLC12A2 (0.33) | SLC12A2SLC12A5FKBP1ACYP1A2CYP2D6 | |
| SCHEMBL21565962 | 0.88 | SLC12A2 (0.37) | SLC12A2SLC12A5CYP1A2CYP2D6 | |
| SCHEMBL9348801 | 0.88 | PLA2G2C (0.35) | PLA2G2CSLC12A2SLC12A5FKBP1ADRD2 | |
| SCHEMBL9348812 | 0.88 | PLA2G2C (0.35) | PLA2G2CSLC12A2SLC12A5FKBP1ADRD2 | |
| SCHEMBL23766543 | 0.87 | SLC12A2 (0.35) | PLA2G2CSLC12A2SLC12A5 | |
| SCHEMBL8074531 | 0.87 | SLC12A2 (0.34) | SLC12A2SLC12A5DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290477-A | Fluoroalkyl phenoxy containing pyrimidine-type compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1994-03-01 | — | — | US | disclosed |