SCHEMBL23766679

SCHEMBL23766679

CCCC(C)(C)c1ccc(OC(F)(F)C(F)(F)C(C)(CC)CC)c(N)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ATM Q13315 2/20 0.39
LMNA P02545 1/20 0.39
CNR1 P21554 8/20 0.36
CNR2 P34972 8/20 0.36
RAB9A P51151 2/20 0.35
NPSR1 Q6W5P4 1/20 0.33
ESR1 P03372 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31
CASP1 P29466 1/20 0.31
HTT P42858 1/20 0.31
CASP7 P55210 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23616399 0.89 L3MBTL1 (0.40) MAPTL3MBTL1ATMLMNACNR1
SCHEMBL23766675 0.86 ESR1 (0.38) CNR1CNR2ESR1
SCHEMBL23766683 0.84 CYP2C19 (0.35) CNR1CNR2
SCHEMBL21791773 0.81 MAPT (0.42) MAPTL3MBTL1ATMLMNACNR1
SCHEMBL25875768 0.79 NPC1 (0.37) MAPTCNR1CNR2RAB9ANPC1
SCHEMBL11706836 0.72 MAPT (0.69) MAPTL3MBTL1ATMLMNARAB9A
SCHEMBL23766643 0.68 NPC1 (0.47) MAPTRAB9AALDH1A1NPC1
SCHEMBL11139060 0.67 MAPK1 (0.41) MAPTCNR1CNR2RAB9ANPSR1
SCHEMBL7048782 0.67 CNR2 (0.54) MAPTL3MBTL1ATMLMNACNR1
SCHEMBL8740742 0.67 MAPT (0.54) MAPTL3MBTL1ATMLMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed
US-20210253786-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2021-08-19 US disclosed