Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18154061 | 0.87 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4OPRM1 | |
| SCHEMBL21210555 | 0.87 | OPRM1 (0.49) | S1PR1S1PR3S1PR5S1PR4OPRM1 | |
| SCHEMBL29758282 | 0.87 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4OPRM1 | |
| SCHEMBL9491709 | 0.85 | S1PR1 (0.47) | S1PR1S1PR3S1PR5S1PR4 | |
| SCHEMBL28143835 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4GBA1 | |
| SCHEMBL28122642 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4GBA1 | |
| SCHEMBL15363013 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4GBA1 | |
| SCHEMBL15363078 | 0.83 | S1PR1 (0.50) | S1PR1S1PR3S1PR5S1PR4GBA1 | |
| SCHEMBL11573927 | 0.83 | OPRM1 (0.46) | S1PR1S1PR3S1PR5S1PR4OPRM1 | |
| SCHEMBL15363084 | 0.82 | S1PR1 (0.45) | S1PR1S1PR3S1PR5S1PR4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021163339-A1 | CATIONIC LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF THERAPEUTICS TO HEPATIC STELLATE CELLS | GENEVANT SCIENCES GMBH (US) | 2021-08-19 | — | — | WO | disclosed |