Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840146 | 0.78 | KDM4E (0.41) | PTPN1 | |
| SCHEMBL863307 | 0.76 | QDPR (0.41) | — | |
| SCHEMBL14731952 | 0.74 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL6127983 | 0.71 | KDM4E (0.38) | — | |
| SCHEMBL24536004 | 0.71 | — | — | |
| SCHEMBL7603813 | 0.71 | — | — | |
| SCHEMBL22893348 | 0.70 | SOS1 (0.35) | — | |
| SCHEMBL6124874 | 0.69 | NAMPT (0.38) | — | |
| SCHEMBL841052 | 0.69 | KDM4E (0.35) | — | |
| SCHEMBL104852 | 0.68 | QDPR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078380-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022078407-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| WO-2021160127-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2021-08-19 | — | — | WO | disclosed |