Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24717656 | 0.82 | RAB9A (0.39) | CRBNALDH1A1TP53 | |
| SCHEMBL20233810 | 0.67 | CRBN (0.62) | CRBNALDH1A1 | |
| SCHEMBL23565386 | 0.67 | CRBN (0.47) | CRBNALDH1A1 | |
| SCHEMBL20153869 | 0.66 | CRBN (0.60) | CRBNALDH1A1 | |
| SCHEMBL21208002 | 0.66 | CRBN (0.60) | CRBNALDH1A1 | |
| SCHEMBL22006673 | 0.66 | CRBN (0.46) | CRBNALDH1A1 | |
| SCHEMBL25469933 | 0.66 | CRBN (0.46) | CRBNALDH1A1 | |
| SCHEMBL23986383 | 0.66 | CRBN (0.46) | CRBNALDH1A1 | |
| SCHEMBL24291413 | 0.66 | CRBN (0.60) | CRBNALDH1A1 | |
| SCHEMBL23565385 | 0.64 | CRBN (0.44) | CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162493-A1 | PROTEIN KINASE DEGRADATION INDUCING COMPOUND, AND USE THEREOF | 보로노이 주식회사 | 2021-08-19 | — | — | WO | disclosed |