Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM5C | P41229 | 2/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032064 | 0.91 | ECE1 (0.58) | ECE1PRMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL16938643 | 0.82 | PRMT1 (0.64) | ECE1PRMT1EGLN1KDM4ELMNA | |
| SCHEMBL10866810 | 0.79 | HDAC3 (0.41) | ECE1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8735106 | 0.78 | ATM (0.52) | ECE1PRMT1HDAC3HDAC4HDAC1 | |
| SCHEMBL8531287 | 0.77 | ECE1 (0.62) | ECE1EGLN1KDM4EKDM5CPHF8 | |
| SCHEMBL10897119 | 0.77 | PRMT1 (0.59) | PRMT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3267882 | 0.75 | PRMT1 (0.63) | PRMT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23567380 | 0.75 | PRMT1 (0.63) | PRMT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL23567470 | 0.75 | PRMT1 (0.63) | PRMT1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL1276363 | 0.75 | HDAC3 (0.41) | ECE1HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912982-A1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | Hangzhou Dac Biotech Co., Ltd (CN) | 2021-11-24 | — | — | EP | disclosed |
| EP-3271329-B1 | NOVEL HYDROPHILIC LINKERS AND LIGAND-DRUG CONJUGATES THEREOF | HANGZHOU DAC BIOTECH CO LTD (CN) | 2021-08-18 | — | — | EP | disclosed |