SCHEMBL3267882

SCHEMBL3267882

O=C(O)CCCCCNC(=O)CBr

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.63
ADRA1A P35348 1/20 0.59
HDAC3 O15379 2/20 0.58
HDAC4 P56524 2/20 0.58
HDAC1 Q13547 2/20 0.58
HDAC7 Q8WUI4 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC10 Q969S8 2/20 0.58
HDAC11 Q96DB2 2/20 0.58
HDAC8 Q9BY41 2/20 0.58
HDAC6 Q9UBN7 2/20 0.58
HDAC9 Q9UKV0 2/20 0.58
HDAC5 Q9UQL6 2/20 0.58
MAPK1 P28482 1/20 0.52
EPHX2 P34913 6/20 0.51
LMNA P02545 3/20 0.50
TSHR P16473 2/20 0.50
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50
PLA2G2A P14555 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23567470 1.00 PRMT1 (0.63) PRMT1ADRA1AHDAC3HDAC4HDAC1
SCHEMBL23567380 1.00 PRMT1 (0.63) PRMT1ADRA1AHDAC3HDAC4HDAC1
SCHEMBL10897119 0.98 PRMT1 (0.59) PRMT1ADRA1AHDAC3HDAC4HDAC1
SCHEMBL8735106 0.91 ATM (0.52) PRMT1ADRA1AHDAC3HDAC4HDAC1
SCHEMBL16853228 0.87 ALDH1A1 (0.59) PRMT1HDAC3HDAC4HDAC1HDAC7
SCHEMBL16853226 0.87 ALDH1A1 (0.59) PRMT1HDAC3HDAC4HDAC1HDAC7
SCHEMBL16853231 0.87 ALDH1A1 (0.59) PRMT1HDAC3HDAC4HDAC1HDAC7
SCHEMBL23475919 0.87 ALDH1A1 (0.59) PRMT1HDAC3HDAC4HDAC1HDAC7
SCHEMBL16853225 0.87 ALDH1A1 (0.59) PRMT1HDAC3HDAC4HDAC1HDAC7
SCHEMBL16853230 0.87 ALDH1A1 (0.59) PRMT1HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10385013-B2 Micro/nano materials, products obtained by covalently modifying surface of micro/nano materials with hydrophilic materials, and method for making same CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) 2019-08-20 US claimed
EP-3470443-A1 MICRO/NANOMATERIAL, PRODUCT THEREOF WITH SURFACE COVALENTLY MODIFIED WITH HYDROPHILIC MATERIAL, AND MANUFACTURING METHOD Chongqing Bolanying (BLY) Biotechnology Co., Ltd., China (CN) 2019-04-17 EP claimed
US-20190077746-A1 MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME CHONGQING BOLANYING (BLY) BIOTECHNOLOGY CO., LTD. (CN) 2019-03-14 US claimed
WO-2001046127-A1 ACYL PSEUDOPEPTIDES BEARING A FUNCTIONALISED AUXILIARY SPACER OM PHARMA (CH) 2001-06-28 WO claimed
EP-0467700-A2 Coconjugate vaccines comprising immunogenic protein, HIV related peptides, and anionic moieties MERCK & CO. INC. (US) 1992-01-22 EP claimed
EP-4661912-A1 LINKER FOR ANTIBODY-DRUG CONJUGATE Pinotbio, Inc. (KR) 2025-12-17 EP disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
US-20240293569-A1 LINKER FOR ANTIBODY-DRUG CONJUGATE PINOTBIO, INC. (KR) 2024-09-05 US disclosed
WO-2024166056-A1 LINKER FOR ANTIBODY-DRUG CONJUGATE PINOTBIO, INC. (KR) 2024-08-15 WO disclosed
EP-4364754-A2 ANTI-B7-H3 ANTIBODIES AND ANTIBODY DRUG CONJUGATES AbbVie Inc. (US) 2024-05-08 EP disclosed
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2024-02-22 US disclosed
US-5606047-A INCLUDES POLYNUCLEOTIDE DUPLEXES THAT HAVE SIGNIFICANT BINDING ACTIVITY FOR LUPUS ANTIBODIES LA JOLLA PHARMACEUTICAL COMPANY (US) 1997-02-25 US disclosed
US-5606030-A IMMUNOGENIC PROTEINS; USEFUL FOR INDUCING ANTI-PEPTIDE IMMUNE RESPONSES IN MAMMALS, HIV-NEUTRALIZING ANTIBODIES IN MAMMALS AND FORMULATING VACCINES TO PREVENT HIV INFECTIONS MERCK & CO., INC. (US) 1997-02-25 US disclosed
US-5552391-A Chemically-defined non-polymeric valency platform molecules and conjugates thereof LA JOLLA PHARMACEUTICAL COMPANY (US) 1996-09-03 US disclosed
EP-0722318-A1 CHEMICALLY-DEFINED NON-POLYMERIC VALENCY PLATFORM MOLECULES AND CONJUGATES THEREOF LA JOLLA PHARMACEUTICAL (US) 1996-07-24 EP disclosed
WO-1995007073-A1 CHEMICALLY-DEFINED NON-POLYMERIC VALENCY PLATFORM MOLECULES AND CONJUGATES THEREOF LA JOLLA PHARMACEUTICAL COMPANY (US) 1995-03-16 WO disclosed
EP-0642798-A2 Chemically-defined non-polymeric valency platform molecules and conjugates thereof LA JOLLA PHARMACEUTICAL COMPANY (CA) 1995-03-15 EP disclosed
EP-0467700-A2 Coconjugate vaccines comprising immunogenic protein, HIV related peptides, and anionic moieties MERCK & CO. INC. (US) 1992-01-22 EP disclosed
US-4897444-A Immobilized fluorogenic substrates for enzymes; and processes for their preparation THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) 1990-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES EGFR, ERBB2, ERBB3 PRMT1 2993/4885ADRA1A 4188/4885HDAC3 1989/4885
US-20240293569-A1 LINKER FOR ANTIBODY-DRUG CONJUGATE BCR, IGSF11, STT3B PRMT1 3185/4885ADRA1A 4395/4885HDAC3 865/4885
US-20190077746-A1 MICRO/NANO MATERIALS, PRODUCTS OBTAINED BY COVALENTLY MODIFYING SURFACE OF MICRO/NANO MATERIALS WITH HYDROPHILIC MATERIALS, AND METHOD FOR MAKING SAME PHOSPHO1, PTMS, PAM PRMT1 481/4885ADRA1A 2899/4885HDAC3 967/4885
US-10385013-B2 Micro/nano materials, products obtained by covalently modifying surface of micro/nano materials with hydrophilic materials, and method for making same PHOSPHO1, PTMS, PAM PRMT1 481/4885ADRA1A 2899/4885HDAC3 967/4885
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 PRMT1 3436/4885ADRA1A 4834/4885HDAC3 1432/4885
US-20240058450-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same BCL2, BAX, BCL9 PRMT1 3436/4885ADRA1A 4834/4885HDAC3 1432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.