Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | TNIK | Q9UKE5 | 9/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978936 | 0.86 | NPC1 (0.44) | ARTNIKMAPK14FAAHTSHR | |
| SCHEMBL29979459 | 0.86 | AR (0.42) | ARTNIKMAPK14FAAHSCN9A | |
| SCHEMBL23769408 | 0.86 | NPC1 (0.44) | ARTNIKMAPK14FAAHTSHR | |
| SCHEMBL23769044 | 0.86 | AR (0.42) | ARTNIKMAPK14FAAHSCN9A | |
| SCHEMBL28914052 | 0.82 | SCN9A (0.50) | ARTNIKSCN9AALDH1A1MAPT | |
| SCHEMBL25028531 | 0.80 | NPC1 (0.48) | FAAHTSHRNPC1RAB9AMAPT | |
| SCHEMBL30895147 | 0.80 | NPC1 (0.48) | FAAHTSHRNPC1RAB9AMAPT | |
| SCHEMBL25138346 | 0.79 | MAOA (0.46) | ARTNIKMAPK14FAAHTSHR | |
| SCHEMBL29978620 | 0.79 | MAOA (0.46) | ARTNIKMAPK14FAAHTSHR | |
| SCHEMBL23768824 | 0.78 | NPC1 (0.44) | ARTNIKMAPK14FAAHSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021161230-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2021-08-19 | — | — | WO | disclosed |