Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769337 | 0.93 | BTK (0.51) | BTKKLKB1L3MBTL1 | |
| SCHEMBL18818263 | 0.90 | BTK (0.62) | BTKKLKB1L3MBTL1 | |
| SCHEMBL23843098 | 0.89 | BTK (0.49) | BTKKLKB1L3MBTL1 | |
| SCHEMBL30140684 | 0.86 | KLKB1 (0.61) | BTKKLKB1 | |
| SCHEMBL20541004 | 0.86 | KLKB1 (0.61) | BTKKLKB1 | |
| SCHEMBL23769242 | 0.85 | BTK (0.49) | BTKKLKB1 | |
| SCHEMBL23769217 | 0.84 | KLKB1 (0.49) | BTKKLKB1L3MBTL1 | |
| SCHEMBL23768875 | 0.84 | KLKB1 (0.48) | BTKKLKB1 | |
| SCHEMBL23768857 | 0.84 | KLKB1 (0.48) | BTKKLKB1L3MBTL1 | |
| SCHEMBL23769334 | 0.83 | KLKB1 (0.47) | BTKKLKB1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |