Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23769240 | 0.80 | — | — | |
| SCHEMBL23769278 | 0.77 | KDM4E (0.32) | — | |
| SCHEMBL23768867 | 0.69 | DPP4 (0.31) | — | |
| SCHEMBL23769276 | 0.69 | DPP4 (0.31) | — | |
| SCHEMBL23769248 | 0.69 | DPP4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL23754084 | 0.68 | DPP4 (0.31) | — | |
| SCHEMBL11501250 | 0.62 | ADORA2B (0.33) | ADORA2B | |
| SCHEMBL11500204 | 0.62 | ADORA2B (0.33) | ADORA2B | |
| SCHEMBL10423669 | 0.58 | ADORA2B (0.46) | ADORA2B | |
| SCHEMBL29653558 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |