Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23843141 | 0.79 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL23769168 | 0.78 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL23769356 | 0.75 | KLKB1 (0.43) | KLKB1 | |
| SCHEMBL29906530 | 0.75 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL23769370 | 0.75 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL23768950 | 0.74 | SMPD3 (0.39) | KLKB1 | |
| SCHEMBL23830164 | 0.72 | KLKB1 (0.39) | KLKB1 | |
| SCHEMBL23769184 | 0.71 | KLKB1 (0.35) | KLKB1 | |
| SCHEMBL23769616 | 0.71 | SMPD3 (0.36) | KLKB1 | |
| SCHEMBL29906547 | 0.71 | KLKB1 (0.44) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160718-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-08-19 | — | — | WO | disclosed |