Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 5/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770777 | 0.83 | ADORA2A (0.33) | ALOX5APFEN1 | |
| SCHEMBL23770609 | 0.82 | CCNT1 (0.32) | CDK9CCNT1 | |
| SCHEMBL23770767 | 0.80 | ALOX5AP (0.34) | ALOX5APFEN1 | |
| SCHEMBL23770438 | 0.78 | KDM4E (0.34) | — | |
| SCHEMBL19925745 | 0.78 | PIK3CG (0.36) | — | |
| SCHEMBL29464316 | 0.78 | PIK3CG (0.36) | — | |
| SCHEMBL23770696 | 0.74 | GAA (0.32) | ABL1 | |
| SCHEMBL23770389 | 0.73 | SCN9A (0.33) | CDK9CCNT1 | |
| SCHEMBL23770641 | 0.73 | ABL1 (0.41) | ABL1 | |
| SCHEMBL23770703 | 0.73 | ABL1 (0.35) | CCNT1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |