Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 16/20 | 0.41 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.38 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770703 | 0.92 | ABL1 (0.35) | ABL1AGPAT2PIK3CDSTIM1ORAI1 | |
| SCHEMBL23770776 | 0.85 | ABL1 (0.38) | ABL1AGPAT2EPHA4 | |
| SCHEMBL23770777 | 0.85 | ADORA2A (0.33) | EPHA4 | |
| SCHEMBL23770438 | 0.80 | KDM4E (0.34) | — | |
| SCHEMBL23770696 | 0.80 | GAA (0.32) | ABL1 | |
| SCHEMBL23770558 | 0.80 | AGPAT2 (0.40) | ABL1AGPAT2EPHA4 | |
| SCHEMBL19968773 | 0.78 | PIK3CD (0.46) | ABL1PIK3CD | |
| SCHEMBL29464429 | 0.78 | PIK3CD (0.46) | ABL1PIK3CD | |
| SCHEMBL23770553 | 0.78 | PIK3CD (0.37) | ABL1PIK3CD | |
| SCHEMBL19925120 | 0.77 | ABL1 (0.46) | ABL1AGPAT2EPHA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |