Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770550 | 0.95 | NOS3 (0.31) | NOS3NOS2 | |
| SCHEMBL23770406 | 0.94 | NOS3 (0.30) | NOS3NOS2 | |
| SCHEMBL23770417 | 0.92 | GAA (0.33) | — | |
| SCHEMBL23770546 | 0.92 | — | — | |
| SCHEMBL23770590 | 0.90 | ADORA2A (0.35) | NOS3NOS2 | |
| SCHEMBL23770693 | 0.89 | PTPN1 (0.30) | — | |
| SCHEMBL23770644 | 0.88 | NOS3 (0.31) | NOS3NOS2 | |
| SCHEMBL23770432 | 0.86 | SCN9A (0.30) | SCN9A | |
| SCHEMBL22338037 | 0.86 | — | — | |
| SCHEMBL23770571 | 0.85 | NOS3 (0.33) | NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |