Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 3/20 | 0.40 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 9/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770715 | 0.93 | AGPAT2 (0.34) | AGPAT2ABL1CTSAMAPK14 | |
| SCHEMBL23770554 | 0.88 | DPP4 (0.33) | MAPK14 | |
| SCHEMBL23770685 | 0.87 | ABL1 (0.37) | AGPAT2EPHA4ABL1CTSAMAPK14 | |
| SCHEMBL23770707 | 0.87 | AGPAT2 (0.39) | AGPAT2ABL1MAPK14 | |
| SCHEMBL23770637 | 0.87 | PDE4B (0.38) | AGPAT2CTSA | |
| SCHEMBL23770590 | 0.87 | ADORA2A (0.35) | EPHA4 | |
| SCHEMBL23770546 | 0.86 | — | — | |
| SCHEMBL23770566 | 0.85 | AGPAT2 (0.35) | AGPAT2EPHA4ABL1 | |
| SCHEMBL23770412 | 0.85 | CCNT1 (0.34) | ABL1 | |
| SCHEMBL23770740 | 0.85 | HSD11B1 (0.33) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |