Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 15/20 | 0.61 |
| ▸ | AXL | P30530 | 8/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.50 |
| ▸ | MERTK | Q12866 | 2/20 | 0.49 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749538 | 0.92 | MET (0.66) | METAXLRETMERTKTYRO3 | |
| SCHEMBL23749463 | 0.86 | MET (0.74) | METAXLRET | |
| SCHEMBL23749415 | 0.86 | MET (0.64) | METAXLRETKDR | |
| SCHEMBL23749369 | 0.85 | MET (0.63) | METAXLMERTKTYRO3KDR | |
| SCHEMBL23749412 | 0.84 | MET (0.67) | METAXLRETMERTKTYRO3 | |
| SCHEMBL23749537 | 0.83 | MET (0.63) | METAXLRETMERTKTYRO3 | |
| SCHEMBL23749455 | 0.83 | MET (0.64) | METAXLRETMERTKTYRO3 | |
| SCHEMBL23749554 | 0.82 | MET (0.65) | METAXLRETMERTKTYRO3 | |
| SCHEMBL23749578 | 0.82 | MET (0.64) | METAXLRETMERTKTYRO3 | |
| SCHEMBL23749555 | 0.81 | AXL (0.67) | METAXLRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865487-A1 | AROMATIC RING-LINKED DIOXANE-QUINAZOLINE OR -QUINOLINE COMPOUNDS, COMPOSITIONS AND USE THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-08-18 | — | — | EP | disclosed |