1,4-Butanediol

1,4-Butanediol

SCHEMBL237716

OCCCCO.OCCO

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
SMN1; SMN2 Q16637 2/20 0.54
ALDH1A1 P00352 3/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GPR84 Q9NQS5 1/20 0.41
FFAR1 O14842 1/20 0.41
FFAR4 Q5NUL3 1/20 0.41
CAMK2A Q9UQM7 1/20 0.38
MIF P14174 1/20 0.35
CA1 P00915 3/20 0.33
CA2 P00918 3/20 0.33
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL11111887 1.00 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL5986604 1.00 TSHR (0.62) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
Ethylene Glycol SCHEMBL3111336 0.94 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL3881899 0.94 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,5-Pentanediol SCHEMBL151905 0.94 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,6-Hexanediol SCHEMBL8519092 0.94 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL4487023 0.94 TSHR (0.56) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,6-Hexanediol SCHEMBL2564661 0.94 TSHR (0.57) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL18642509 0.94 SMN1; SMN2 (0.58) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10
1,4-Butanediol SCHEMBL324322 0.94 SMN1; SMN2 (0.58) TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215535-A Apparatus and method for producing polyester depolymerization and apparatus and method for producing polyester 伍德依文达菲瑟有限责任公司 2024-06-18 CN claimed
CN-116693801-A Zwitterionic polyurethane and preparation method and application of zwitterionic polyurethane-based ionic gel 浙江禾欣新材料有限公司 2023-09-05 CN claimed
CN-108571582-B Method for lubricating surfaces 英菲诺姆国际有限公司 2023-07-04 CN claimed
CN-109196064-B Antifouling coating composition, antifouling coating film, laminated antifouling coating film, substrate with antifouling coating film, method for producing same, and antifouling method 中国涂料株式会社 2021-09-28 CN claimed
CN-107245317-B Moisture-curing polyurethane hot melt adhesive and preparation method thereof 广州千顺工业材料有限公司 2021-06-22 CN claimed
CN-106886127-B Photoimprint resin composition, photoimprint resin film, and patterning process 财团法人工业技术研究院 2020-09-01 CN claimed
US-10698233-B2 Contact lens LARGAN MEDICAL CO., LTD. (TW) 2020-06-30 US claimed
CN-106932920-B Contact lens 星欧光学股份有限公司 2020-01-03 CN claimed
CN-110366572-A Shock proof thermoplastic polyurethane, its preparation and use 科思创德国股份有限公司 2019-10-22 CN claimed
CN-110218290-A A kind of synthetic method of tough, transparent, fluorescence, antimicrobial polyurethane films 西安交通大学 2019-09-10 CN claimed
US-20170192251-A1 CONTACT LENS LARGAN MEDICAL CO., LTD. (TW) 2017-07-06 US claimed
CN-103965781-B Enzyme modified natural raw lacquer composition and method of making the same CENTRAL SOUTH UNIVERSITY OF FORESTRY AND TECHNOLOGY (CN) 2016-01-20 CN claimed
CN-103965781-A Bio-enzyme modified natural raw lacquer composition and preparation method thereof UNIV CENTRAL SOUTH FORESTRY 2014-08-06 CN claimed
CN-103814095-A Pressure sensitive adhesive composition for protective film having antistatic property and method for preparing the same LG CHEMICAL LTD 2014-05-21 CN claimed
US-8138299-B2 Hardness below 80 Shore A; preferably transparent and plasticizer-free; Polyesterurethane made by reacting an isocyanate with two polyesterdiols, the first having 1,4-butanediol units and another C5+ diol, and the second having 1,4-butanediol units and a C2-3 diol such as ethylene glycol; nonshrinking BASF AKTIENGESELLSCHAFT (DE) 2012-03-20 US claimed
EP-1877460-B1 THERMOPLASTIC POLYURETHANES BASF SE (DE) 2009-02-18 EP claimed
US-20080194789-A1 Thermoplastic Polyurethanes BASF AKTIENGESELLSCHAFT (DE) 2008-08-14 US claimed
EP-1611177-B1 MELT SPUN TPU FIBERS AND PROCESS LUBRIZOL ADVANCED MAT INC (US) 2008-02-06 EP claimed
US-20070148423-A1 Biaxially stretched laminated polyester film and polyester film for covering MITSUBISHI POLYESTER FILM CORPORATION (JP) 2007-06-28 US claimed
EP-1169025-B1 TRANSDERMAL DRUG DELIVERY DEVICES COMPRISING A POLYURETHANE DRUG RESERVOIR ALZA CORP (US) 2005-08-24 EP claimed