SCHEMBL23771990

SCHEMBL23771990

CC(C)NC(CCCCNC(=O)CCc1cn(C(C)C)nn1)C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALB P02768 2/20 0.41
FOLH1 Q04609 8/20 0.41
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
RAD52 P43351 1/20 0.35
PARP14 Q460N5 1/20 0.35
NR2F2 P24468 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24618033 0.85 GRIN1 (0.40) ALBFOLH1MEN1KMT2APOLB
SCHEMBL24617914 0.85 GRIN1 (0.40) ALBFOLH1MEN1KMT2APOLB
SCHEMBL24622267 0.85 GRIN1 (0.40) ALBFOLH1MEN1KMT2APOLB
SCHEMBL24618034 0.85 GRIN1 (0.40) ALBFOLH1MEN1KMT2APOLB
SCHEMBL24617923 0.85 GRIN1 (0.40) ALBFOLH1MEN1KMT2APOLB
SCHEMBL24617920 0.85 GRIN1 (0.40) ALBFOLH1MEN1KMT2APOLB
SCHEMBL24618010 0.85 FOLH1 (0.43) ALBFOLH1PARP14
SCHEMBL24618028 0.85 FOLH1 (0.43) ALBFOLH1PARP14
SCHEMBL24618012 0.85 NR2F2 (0.41) ALBFOLH1MEN1KMT2APOLB
SCHEMBL26225557 0.84 ALB (0.39) ALBFOLH1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331801-A1 IL-2R-BETA-GAMMA BINDING COMPOUNDS MEDIKINE, INC. (US) 2023-10-19 US disclosed
US-11718654-B2 IL-2R-βγ binding compounds MEDIKINE, INC. (US) 2023-08-08 US disclosed
US-20210253670-A1 IL-7R-ALPHA-GAMMA BINDING COMPOUNDS BLUEBIRD VENTURES I, L.P. 2021-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331801-A1 IL-2R-BETA-GAMMA BINDING COMPOUNDS IL2RA, IL2, IL15RA ALB 1363/4885FOLH1 2443/4885MEN1 4744/4885
US-20210253670-A1 IL-7R-ALPHA-GAMMA BINDING COMPOUNDS IL2RA, IL2, IL6ST ALB 1918/4885FOLH1 3432/4885MEN1 4155/4885
US-11718654-B2 IL-2R-βγ binding compounds IL2RA, IL2, IL1RN ALB 2282/4885FOLH1 2905/4885MEN1 4760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.