Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.43 |
| ▸ | PADI1 | Q9ULC6 | 4/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.43 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 3/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24618028 | 1.00 | FOLH1 (0.43) | FOLH1PADI1PADI4PDE4APADI2 | |
| SCHEMBL24700306 | 0.91 | GRIN1 (0.45) | FOLH1ALBTPSAB1GRIN1GRIN2A | |
| SCHEMBL23771990 | 0.85 | ALB (0.41) | FOLH1ALBPARP14 | |
| SCHEMBL24700098 | 0.84 | ALB (0.39) | FOLH1ALB | |
| SCHEMBL24617914 | 0.81 | GRIN1 (0.40) | FOLH1ALBGRIN1GRIN2A | |
| SCHEMBL24618033 | 0.81 | GRIN1 (0.40) | FOLH1ALBGRIN1GRIN2A | |
| SCHEMBL24622267 | 0.81 | GRIN1 (0.40) | FOLH1ALBGRIN1GRIN2A | |
| SCHEMBL24617923 | 0.81 | GRIN1 (0.40) | FOLH1ALBGRIN1GRIN2A | |
| SCHEMBL24618034 | 0.81 | GRIN1 (0.40) | FOLH1ALBGRIN1GRIN2A | |
| SCHEMBL24617920 | 0.81 | GRIN1 (0.40) | FOLH1ALBGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022195287-A9 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 | BICYCLETX LIMITED (GB) | 2022-10-20 | — | — | WO | disclosed |
| WO-2022148970-A1 | ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS | BICYCLETX LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |