Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26497621 | 0.89 | TYK2 (0.78) | TYK2 | |
| SCHEMBL23772359 | 0.82 | TYK2 (0.62) | TYK2 | |
| SCHEMBL21948515 | 0.81 | TYK2 (0.52) | TYK2 | |
| SCHEMBL20688813 | 0.80 | TYK2 (0.79) | TYK2 | |
| SCHEMBL23753630 | 0.79 | TYK2 (0.83) | TYK2 | |
| SCHEMBL20688163 | 0.78 | TYK2 (1.00) | TYK2 | |
| SCHEMBL21947780 | 0.77 | TYK2 (1.00) | TYK2 | |
| SCHEMBL29754351 | 0.77 | TYK2 (1.00) | TYK2 | |
| SCHEMBL21961750 | 0.76 | TYK2 (0.79) | TYK2 | |
| SCHEMBL21726967 | 0.75 | TYK2 (0.87) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162942-A1 | 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2021-08-19 | — | — | WO | disclosed |