Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.62 |
| ▸ | JAK1 | P23458 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23772279 | 0.82 | TYK2 (0.63) | TYK2 | |
| SCHEMBL23753630 | 0.80 | TYK2 (0.83) | TYK2JAK1 | |
| SCHEMBL23772121 | 0.80 | TYK2 (0.69) | TYK2JAK1 | |
| SCHEMBL23772276 | 0.78 | TYK2 (0.64) | TYK2 | |
| SCHEMBL21726967 | 0.78 | TYK2 (0.87) | TYK2JAK1 | |
| SCHEMBL20697087 | 0.78 | TYK2 (0.81) | TYK2JAK1 | |
| SCHEMBL20678905 | 0.77 | TYK2 (0.79) | TYK2JAK1 | |
| SCHEMBL20688163 | 0.77 | TYK2 (1.00) | TYK2 | |
| SCHEMBL20688348 | 0.77 | TYK2 (1.00) | TYK2JAK1 | |
| SCHEMBL20688563 | 0.77 | TYK2 (1.00) | TYK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021162942-A1 | 7-(METHYLAMINO)PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2021-08-19 | — | — | WO | disclosed |