Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | ADH1B | P00325 | 3/20 | 0.46 |
| ▸ | ADH1A | P07327 | 3/20 | 0.46 |
| ▸ | ADH7 | P40394 | 3/20 | 0.46 |
| ▸ | ADH1C | P00326 | 2/20 | 0.46 |
| ▸ | ADH4 | P08319 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140723 | 0.91 | TSHR (0.71) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL258536 | 0.91 | TSHR (0.71) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL10582942 | 0.91 | TSHR (0.71) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL24490479 | 0.91 | TSHR (0.58) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL3692351 | 0.91 | TSHR (0.71) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL345043 | 0.88 | — | — | |
| Dipentylamine SCHEMBL27643254 | 0.88 | TSHR (0.87) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL28952801 | 0.86 | TSHR (0.72) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL117275 | 0.85 | TSHR (0.81) | TSHRALDH1A1EPHX1S1PR2S1PR4 | |
| SCHEMBL9801424 | 0.85 | TSHR (0.81) | TSHRALDH1A1EPHX1S1PR2S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210251848-A1 | TREATMENT OF BLEEDING BY NON-INVASIVE STIMULATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-08-19 | — | — | US | disclosed |