SCHEMBL117275

SCHEMBL117275

CCCCCCCCCCCCCCCCCCCCCCCCCNCCC

nearest known ligand 0.81

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.81
ALDH1A1 P00352 1/20 0.81
EPHX1 P07099 4/20 0.55
ADH1B P00325 1/20 0.55
ADH1C P00326 1/20 0.55
ADH1A P07327 1/20 0.55
ADH4 P08319 1/20 0.55
ADH7 P40394 1/20 0.55
S1PR2 O95136 5/20 0.54
S1PR4 O95977 5/20 0.54
S1PR1 P21453 5/20 0.54
S1PR3 Q99500 5/20 0.54
S1PR5 Q9H228 1/20 0.54
PAOX Q6QHF9 1/20 0.52
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
THRB P10828 1/20 0.50
PPARA Q07869 2/20 0.48
SIGMAR1 Q99720 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1575855 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL386694 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL2584239 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL1396468 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL4958373 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL2845493 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL1204398 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL9801424 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL21611681 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C
SCHEMBL5467592 1.00 TSHR (0.81) TSHRALDH1A1EPHX1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605325-B2 Hair styling compositions for improving the elongation of hair curls L'OREAL (FR) 2026-04-21 US disclosed
US-12599546-B2 Hair treatment compositions, kits thereof, and methods thereof L'OREAL (FR) 2026-04-14 US disclosed
US-12589065-B2 Hair care system, hair care method and use of a hair care system L'OREAL (FR) 2026-03-31 US disclosed
US-12551422-B2 Compositions and methods for styling the hair L'ORÉAL (FR) 2026-02-17 US disclosed
US-20260000583-A1 COSMETIC KIT WITH A CLEANSING STICK, DISPENSING CONTAINER, AND CUTTING DEVICE L'OREAL (FR) 2026-01-01 US disclosed
US-20250367104-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN L'OREAL (FR) 2025-12-04 US disclosed
US-20250367103-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN L'OREAL (FR) 2025-12-04 US disclosed
EP-4633589-A1 HAIR TREATMENT COMPOSITIONS THAT IMPART SHINE AND LUSTER L'OREAL (FR) 2025-10-22 EP disclosed
US-20250302716-A1 HAIR TREATMENT SERUM AND METHOD OF USE L'OREAL (FR) 2025-10-02 US disclosed
US-12383483-B2 Compositions and methods for styling the hair L'OREAL (FR) 2025-08-12 US disclosed
EP-2272496-A1 Composition and method for levelling hair colour KPSS-Kao Professional Salon Services GmbH (DE) 2011-01-12 EP disclosed
EP-2258337-A1 Composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-12-08 EP disclosed
WO-2010124817-A2 CONDITIONING COMPOSITION FOR HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-11-04 WO disclosed
EP-2246033-A1 Conditioning composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-11-03 EP disclosed
WO-2010069501-A1 COSMETIC COMPOSITION FOR HAIR AND SCALP KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-06-24 WO disclosed
EP-2196178-A1 Cosmetic composition for hair and scalp KPSS-Kao Professional Salon Services GmbH (DE) 2010-06-16 EP disclosed
WO-2010060601-A1 BLEACHING/HIGHLIGHTING COMPOSITION KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-06-03 WO disclosed
EP-2191812-A1 Bleaching/Highlighting composition KPSS-Kao Professional Salon Services GmbH (DE) 2010-06-02 EP disclosed
WO-2010025894-A2 CONDITIONING COMPOSITION FOR HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2010-03-11 WO disclosed
EP-2161016-A1 Conditioning composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2010-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367104-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN CUTA, DSG1, POLG TSHR 4644/4885ALDH1A1 1297/4885EPHX1 2040/4885
US-12605325-B2 Hair styling compositions for improving the elongation of hair curls SGMS1, SGMS2, SGPL1 TSHR 2285/4885ALDH1A1 3737/4885EPHX1 3529/4885
US-12551422-B2 Compositions and methods for styling the hair DPM1, PIK3C3, SMURF1 TSHR 2988/4885ALDH1A1 4044/4885EPHX1 3663/4885
US-12589065-B2 Hair care system, hair care method and use of a hair care system ASH2L, ALG3, PLOD3 TSHR 2630/4885ALDH1A1 3848/4885EPHX1 3028/4885
US-12599546-B2 Hair treatment compositions, kits thereof, and methods thereof EBP, FHIT, BRDT TSHR 3668/4885ALDH1A1 969/4885EPHX1 3956/4885
US-20260000583-A1 COSMETIC KIT WITH A CLEANSING STICK, DISPENSING CONTAINER, AND CUTTING DEVICE CUTA, PRKDC, PRKACG TSHR 3423/4885ALDH1A1 1769/4885EPHX1 2295/4885
US-20250367103-A1 SOLIDIFIED GEL AND METHODS FOR CLEANSING SKIN CUTA, DSG1, POLG TSHR 4644/4885ALDH1A1 1297/4885EPHX1 2040/4885
US-12383483-B2 Compositions and methods for styling the hair SGMS1, SGMS2, DPM1 TSHR 3112/4885ALDH1A1 3976/4885EPHX1 3503/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.