SCHEMBL23773152

SCHEMBL23773152

CCOC(O)OCCNC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32
CPB2 Q96IY4 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866329 0.77
SCHEMBL4146828 0.74
SCHEMBL22609583 0.73
SCHEMBL5611395 0.73
SCHEMBL14844068 0.73
SCHEMBL27590446 0.71
SCHEMBL7712111 0.71 TSHR (0.37) THRBLMNA
SCHEMBL28960216 0.70
SCHEMBL3421349 0.69 HTR1D (0.32) CPB2
SCHEMBL10609163 0.68 LMNA (0.36) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3865482-A1 7-SUBSTITUTED SULFONIMIDOYLPURINONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION F. Hoffmann-La Roche AG (CH) 2021-08-18 EP disclosed