SCHEMBL2377321

SCHEMBL2377321

C1[N]CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149034 0.76
SCHEMBL363669 0.68
Aziridine SCHEMBL16878816 0.51
Aziridine SCHEMBL3089497 0.51
SCHEMBL182191 0.51
Aziridine SCHEMBL2267 0.51
SCHEMBL4070 0.51
SCHEMBL576335 0.46 HIF1A (1.00)
SCHEMBL44386 0.46
SCHEMBL2373879 0.46 HIF1A (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399204-A1 POTENT AND SELECTIVE INHIBITORS OF IRAK4 Dana-Farber Cancer Institute, Inc. (US) 2024-07-17 EP disclosed
US-20240217983-A1 GPR119 AGONISTS KALLYOPE, INC. 2024-07-04 US disclosed
EP-4334289-A1 NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF Organon R&D Finland Ltd (FI) 2024-03-13 EP disclosed
EP-4320129-A1 GPR119 AGONISTS Kallyope, Inc. (US) 2024-02-14 EP disclosed
EP-4313985-A2 HETEROCYCLIC COMPOUNDS AND THEIR USE Equinorm Ltd (FI) 2024-02-07 EP disclosed
EP-3871673-B1 NOVEL INDAZOLE COMPOUND OR SALT THEREOF TAIHO PHARMACEUTICAL CO LTD (JP) 2024-01-03 EP disclosed
US-11834467-B2 Substituted indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors 1ST Biotherapeutics, Inc. (KR) 2023-12-05 US disclosed
US-20230365557-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS 1ST Biotherapeutics, Inc. (KR) 2023-11-16 US disclosed
US-11802126-B2 Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders 1ST Biotherapeutics, Inc. (KR) 2023-10-31 US disclosed
US-20230339978-A1 COMPOUNDS FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISORDERS 1ST Biotherapeutics, Inc. (KR) 2023-10-26 US disclosed
WO-2019070093-A1 BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS 1ST Biotherapeutics, Inc. (KR) 2019-04-11 WO disclosed
US-20190100500-A1 BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS 1ST Biotherapeutics, Inc. 2019-04-04 US disclosed
EP-2980906-A1 Fluorinated carbamates as solvent for lithium-ion electrolytes Westfälische Wilhelms-Universität Münster (DE) 2016-02-03 EP disclosed
US-20110230419-A1 IAP BINDING COMPOUNDS NUEVOLUTION A/S (DK) 2011-09-22 US disclosed
EP-0887874-B1 Electrolyte for lithium batteries and its use, and method for increasing the safety of lithium batteries SOLVAY FLUOR GMBH (DE) 2010-09-22 EP disclosed
US-6489064-B2 LITHIUM-CONTAINING CONDUCTIVE SALT AND ELECTROLYTE LIQUID COMPRISING AN EFFECTIVE AMOUNT OF PARTIALLY FLUORINATED AMIDE SOLVAY FLUOR UND DERIVATE GMBH (DE) 2002-12-03 US disclosed
EP-1153450-B1 ELECTROLYTE SYSTEM FOR LITHIUM BATTERIES, THE USE THEREOF AND METHOD FOR ENHANCING SAFETY OF LITHIUM BATTERIES SOLVAY FLUOR & DERIVATE (DE) 2002-10-16 EP disclosed
US-20020042003-A1 Lithium-containing conductive salt and electrolyte liquid comprising an effective amount of partially fluorinated amide SOLVAY FLUOR UND DERIVATE GMBH (DE) 2002-04-11 US disclosed
US-6159640-A Electrolyte system for lithium batteries and use of said system, and method for increasing the safety of lithium batteries HOECHST RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) 2000-12-12 US disclosed
EP-0887874-A2 Electrolyte for lithium batteries and its use, and method for increasing the safety of lithium batteries Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) 1998-12-30 EP disclosed