SCHEMBL576335

SCHEMBL576335

C1CNCCNCCNCCNCCNCCN1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 1.00
MAPT P10636 1/20 1.00
PDE4A P27815 1/20 1.00
KDR P35968 1/20 1.00
CXCR4 P61073 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
ALDH1A1 P00352 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
CYP2C9 P11712 1/20 0.50
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4299924 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL577429 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL8199316 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL22003 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL7052601 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL5033222 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL2373879 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
Piperazine SCHEMBL734764 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
SCHEMBL3999265 1.00 HIF1A (1.00) HIF1AMAPTPDE4AKDRCXCR4
Piperazine SCHEMBL8010246 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 538 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12428362-B2 Method for preparing acrylic acid from beta- propiolactone COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2025-09-30 US claimed
EP-3940806-B1 METHOD OF MODIFYING THE STRUCTURE OF PEROVSKITE FILMS ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) 2023-08-16 EP claimed
US-20230192585-A1 METHOD FOR PREPARING ACRYLIC ACID FROM BETA-PROPIOLACTONE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-06-22 US claimed
US-20230182088-A1 METHOD FOR PREPARING HIGH-SELECTIVITY LITHIUM-MAGNESIUM SEPARATION MEMBRANE TIANJIN UNIVERSITY (CN) 2023-06-15 US claimed
CN-116211887-A Composition for treating acid-base imbalance 特里赛达公司 2023-06-06 CN claimed
EP-4153556-A1 METHOD FOR PREPARING ACRYLIC ACID FROM BETA-PROPIOLACTONE Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2023-03-29 EP claimed
US-11591225-B2 Method for producing carbon monoxide COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-02-28 US claimed
EP-3940806-A1 METHOD OF MODIFYING THE STRUCTURE OF PEROVSKITE FILMS Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) 2022-01-19 EP claimed
WO-2021233839-A1 METHOD FOR PREPARING ACRYLIC ACID FROM β-PROPIOLACTONE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2021-11-25 WO claimed
US-20210188650-A1 METHOD FOR PRODUCING CARBON MONOXIDE COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2021-06-24 US claimed
US-20040122250-A1 Mesoporous organic-inorganic hybrid materials for separating gases CENTRE NATIONAL DE LA RECHERCHE-SCIENTIFIQUE (FR) 2004-06-24 US claimed
US-5759518-A Metal complexes of dendrimeric macromolecules, diagnostics agents that contain the latter as well as process for the production of the complexes and agents SCHERING AKTIENGESELLSCHAFT (DE) 1998-06-02 US claimed
US-5702804-A Recording sheets XEROX CORPORATION (US) 1997-12-30 US claimed
EP-0618910-A1 SYNTHESIS OF POLYAZAMACROCYCLES WITH MORE THAN ONE TYPE OF SIDE-CHAIN CHELATING GROUPS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-10-12 EP claimed
WO-1993012097-A1 SYNTHESIS OF POLYAZAMACROCYCLES WITH MORE THAN ONE TYPE OF SIDE-CHAIN CHELATING GROUPS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-06-24 WO claimed
EP-0325307-B1 MACROCYCLIC POLYAMINE MULTIFUNCTIONAL LUBRICATING OIL ADDITIVES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-02-03 EP claimed
WO-1990007261-A2 PROCESS FOR PREPARING MONO-N-ALKYLATED POLYAZAMACROCYCLES THE DOW CHEMICAL COMPANY (US) 1990-07-12 WO claimed
EP-0325307-A2 Macrocyclic polyamine multifunctional lubricating oil additives EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-07-26 EP claimed
EP-0113582-A2 Macrocyclic polyamine and polycyclic polyamine multifunctional lubricating oil additives EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-07-18 EP claimed
US-4001212-A EXTRACT METAL IONS FROM SOLUTION AND COMPLEX E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11591225-B2 Method for producing carbon monoxide ALDOA, CYP4A11, ADH1A HIF1A 435/4885MAPT 1179/4885PDE4A 2944/4885
US-20210188650-A1 METHOD FOR PRODUCING CARBON MONOXIDE ALDOA, CYP4A11, ADH1A HIF1A 435/4885MAPT 1179/4885PDE4A 2944/4885
US-20040122250-A1 Mesoporous organic-inorganic hybrid materials for separating gases SCO2, IPO9, IPO4 HIF1A 3377/4885MAPT 4676/4885PDE4A 4882/4885
US-20230192585-A1 METHOD FOR PREPARING ACRYLIC ACID FROM BETA-PROPIOLACTONE ALAD, PCCA, APEH HIF1A 1219/4885MAPT 2286/4885PDE4A 3432/4885
US-12428362-B2 Method for preparing acrylic acid from beta- propiolactone ALAD, PCCA, APEH HIF1A 1219/4885MAPT 2286/4885PDE4A 3432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.