⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL3262873 | 0.66 | — | — | |
| SCHEMBL5855559 | 0.61 | — | — | |
| SCHEMBL1419 | 0.61 | — | — | |
| SCHEMBL3273283 | 0.58 | NOS3 (0.30) | — | |
| SCHEMBL9808297 | 0.58 | NOS3 (0.30) | — | |
| SCHEMBL206353 | 0.58 | NOS3 (0.30) | — | |
| SCHEMBL495581 | 0.58 | — | — | |
| SCHEMBL4294 | 0.58 | — | — | |
| SCHEMBL6575355 | 0.58 | NOS3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399204-A1 | POTENT AND SELECTIVE INHIBITORS OF IRAK4 | Dana-Farber Cancer Institute, Inc. (US) | 2024-07-17 | — | — | EP | disclosed |
| US-20240217983-A1 | GPR119 AGONISTS | KALLYOPE, INC. | 2024-07-04 | — | — | US | disclosed |
| EP-4334289-A1 | NOVEL HETEROCYCLIC COMPOUNDS, COMPOSITIONS, METHODS OF PREPARATION AND USES THEREOF | Organon R&D Finland Ltd (FI) | 2024-03-13 | — | — | EP | disclosed |
| EP-4320129-A1 | GPR119 AGONISTS | Kallyope, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| EP-4313985-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE | Equinorm Ltd (FI) | 2024-02-07 | — | — | EP | disclosed |
| EP-3871673-B1 | NOVEL INDAZOLE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2024-01-03 | — | — | EP | disclosed |
| US-11834467-B2 | Substituted indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors | 1ST Biotherapeutics, Inc. (KR) | 2023-12-05 | — | — | US | disclosed |
| US-20230365557-A1 | IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | 1ST Biotherapeutics, Inc. (KR) | 2023-11-16 | — | — | US | disclosed |
| US-11802126-B2 | Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders | 1ST Biotherapeutics, Inc. (KR) | 2023-10-31 | — | — | US | disclosed |
| US-20230339978-A1 | COMPOUNDS FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISORDERS | 1ST Biotherapeutics, Inc. (KR) | 2023-10-26 | — | — | US | disclosed |
| EP-3692023-A1 | BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS | 1st Biotherapeutics, Inc. (KR) | 2020-08-12 | — | — | EP | disclosed |
| CN-111479813-A | Triazolobenzazepines as vasopressin V1A receptor antagonists | 吉瑞工厂 | 2020-07-31 | — | — | CN | disclosed |
| CN-111315727-A | Benzothiazole compounds and methods of using the same for treating neurodegenerative diseases | 第一生物治疗股份有限公司 | 2020-06-19 | — | — | CN | disclosed |
| US-10669246-B2 | Benzothiazol compounds and methods using the same for treating neurodegenerative disorders | 1ST Biotherapeutics, Inc. (KR) | 2020-06-02 | — | — | US | disclosed |
| US-20200079757-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | THE UNIVERSITY OF MELBOURNE (AU) | 2020-03-12 | — | — | US | disclosed |
| WO-2019070093-A1 | BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS | 1ST Biotherapeutics, Inc. (KR) | 2019-04-11 | — | — | WO | disclosed |
| US-20190100500-A1 | BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS | 1ST Biotherapeutics, Inc. | 2019-04-04 | — | — | US | disclosed |
| EP-2980906-A1 | Fluorinated carbamates as solvent for lithium-ion electrolytes | Westfälische Wilhelms-Universität Münster (DE) | 2016-02-03 | — | — | EP | disclosed |
| US-20110230419-A1 | IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-6159640-A | Electrolyte system for lithium batteries and use of said system, and method for increasing the safety of lithium batteries | HOECHST RESEARCH & TECHNOLOGY GMBH & CO. KG (DE) | 2000-12-12 | — | — | US | disclosed |