Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | ADA | P00813 | 4/20 | 0.45 |
| ▸ | PDE2A | O00408 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946798 | 0.88 | ADORA2A (0.68) | ADORA2AADORA2BADORA1ADAPDE2A | |
| SCHEMBL11243630 | 0.84 | ADORA2A (0.51) | ADORA2AADORA2BADORA1ADAPDE2A | |
| SCHEMBL21539425 | 0.82 | ADORA2A (0.78) | ADORA2AADORA2BADORA1ADAPDE2A | |
| SCHEMBL18751223 | 0.80 | ADORA2A (0.64) | ADORA2AADORA2BADORA1CCNB2CDK1 | |
| SCHEMBL22381514 | 0.79 | CYP1A2 (0.55) | ADORA2AADORA2BADORA1ADAPDE2A | |
| Nosantine SCHEMBL11253031 | 0.77 | ADA (0.76) | ADAPDE2ACYP3A4PDE4APDE4B | |
| Nosantine SCHEMBL1740450 | 0.76 | PDE2A (0.77) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL22381495 | 0.74 | ADORA2A (0.74) | ADORA2AADORA2BADORA1ADAPDE2A | |
| SCHEMBL21118434 | 0.72 | ADORA2A (0.72) | ADORA2AADORA2BADORA1ADAPDE2A | |
| SCHEMBL15214191 | 0.72 | ADORA2A (0.43) | ADORA2AADORA2BADORA1ADAPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210251887-A1 | INJECTABLE FORMULATIONS FOR TREATING CANCER | Epizyme, Inc. | 2021-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210251887-A1 | INJECTABLE FORMULATIONS FOR TREATING CANCER | DOT1L, PRMT1, MECP2 | ADORA2A 2513/4885ADORA2B 2493/4885ADORA1 1185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.