Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.68 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | CCNB2 | O95067 | 7/20 | 0.45 |
| ▸ | CDK1 | P06493 | 7/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.45 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.45 |
| ▸ | ADA | P00813 | 4/20 | 0.41 |
| ▸ | PDE2A | O00408 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23774610 | 0.88 | ADORA2A (0.52) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL11243630 | 0.87 | ADORA2A (0.51) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL18751223 | 0.83 | ADORA2A (0.64) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL23867105 | 0.82 | ADORA2A (0.69) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL240049 | 0.81 | ADORA2A (1.00) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL233401 | 0.81 | ADORA2A (1.00) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL4572183 | 0.81 | ADORA2A (1.00) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL21943154 | 0.78 | ADORA2A (0.64) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL19661692 | 0.78 | ADORA2A (0.64) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL21943153 | 0.77 | CDK1 (0.61) | ADORA2AADORA2BADORA1CCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739325-B2 | Oligonucleotide compositions and methods thereof | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-29 | — | — | US | disclosed |
| US-20210032620-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-02-04 | — | — | US | disclosed |