Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23775752 | 0.83 | SMN1; SMN2 (0.48) | MAPTHPGDKMT2ASMN1; SMN2HTT | |
| SCHEMBL4969852 | 0.79 | MAPT (0.51) | MAPTHSD11B1ALDH1A1HPGDGAA | |
| SCHEMBL25920373 | 0.72 | POLB (0.53) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL28470729 | 0.71 | SNCA (0.50) | MAPTHPGDGAAMEN1KMT2A | |
| SCHEMBL30467250 | 0.71 | SNCA (0.50) | MAPTHPGDGAAMEN1KMT2A | |
| SCHEMBL24124669 | 0.71 | POLB (0.70) | MAPTALDH1A1GAASMN1; SMN2HTT | |
| SCHEMBL15586614 | 0.70 | EPHX2 (0.63) | ALDH1A1HPGDHTTHSD17B10GFER | |
| SCHEMBL17807750 | 0.70 | MAOB (0.47) | MAPTHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14804455 | 0.69 | GAA (0.33) | ALDH1A1HPGDGAASMN1; SMN2HTT | |
| SCHEMBL20251044 | 0.68 | PGR (0.50) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160132-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2021-08-19 | — | — | WO | disclosed |