Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 6/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 5/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23775849 | 0.87 | PLAU (0.50) | PLAUPRSS1F2F10F7 | |
| SCHEMBL23775851 | 0.84 | PLAU (0.47) | PLAUPRSS1F2F10F7 | |
| SCHEMBL14599569 | 0.84 | PLAU (0.51) | PLAUPRSS1CHEK2F2F10 | |
| SCHEMBL23775610 | 0.81 | F2 (0.50) | PLAUPRSS1F2F10F7 | |
| SCHEMBL23775790 | 0.81 | PLAU (0.51) | PLAUPRSS1F2F10F7 | |
| SCHEMBL23775814 | 0.81 | PLAU (0.48) | PLAUPRSS1F2F10F7 | |
| Hydrochloric Acid SCHEMBL11298806 | 0.80 | PLAU (0.65) | PLAUPRSS1F2F10F7 | |
| SCHEMBL7879342 | 0.80 | PLAU (0.65) | PLAUPRSS1F2F10F7 | |
| SCHEMBL12348331 | 0.78 | CHEK2 (0.42) | PLAUPRSS1CHEK2 | |
| SCHEMBL12348336 | 0.78 | PLAU (0.48) | PLAUPRSS1F2F10F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160132-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2021-08-19 | — | — | WO | disclosed |