Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 6/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.65 |
| ▸ | PLG | P00747 | 5/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.58 |
| ▸ | F7 | P08709 | 1/20 | 0.58 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11298806 | 0.97 | PLAU (0.65) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL21017925 | 0.94 | PLAU (0.61) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL14599542 | 0.91 | PLAU (0.79) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL5396848 | 0.89 | PLAU (0.60) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL5401865 | 0.89 | PLAU (0.56) | PLAUPRSS1PLGF2F10 | |
| Hydrochloric Acid SCHEMBL29202497 | 0.89 | F2 (0.68) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL23775704 | 0.88 | PLAU (0.59) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL15986650 | 0.88 | PLAU (0.56) | PLAUPRSS1PLG | |
| SCHEMBL23901826 | 0.88 | PLAU (0.55) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL8608936 | 0.88 | HDAC6 (0.57) | PLAUPRSS1PLGF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329412-B1 | TREATING NEOPLASTIC DISEASE ASSOCIATED WITH INCREASED LEVELS OF DNA METHYLATION USING DNA METHYLTRANSFERASE INHIBITOR | PFIZER INC | 2001-12-11 | — | — | US | claimed |