Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26979271 | 1.00 | LMNA (0.68) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL23118203 | 1.00 | LMNA (0.68) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL23779761 | 1.00 | LMNA (0.68) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL23118202 | 1.00 | LMNA (0.68) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL13716536 | 0.90 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL21138671 | 0.90 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL21058368 | 0.90 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL30032874 | 0.90 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL25957762 | 0.90 | LMNA (0.65) | LMNAKMT2APOLBALDH1A1CYP2D6 | |
| SCHEMBL24294515 | 0.89 | LMNA (0.56) | LMNAKMT2APOLBALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226332-B | Bivalent targeting conjugates | 阿布特斯生物制药公司 | 2025-05-09 | — | — | CN | disclosed |
| US-20220062323-A1 | BIVALENT TARGETED CONJUGATES | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-03-03 | — | — | US | disclosed |
| US-20220031847-A1 | THERAPEUTIC METHODS | GENEVANT SCIENCES GMBH (CH) | 2022-02-03 | — | — | US | disclosed |
| EP-3873486-A1 | BIVALENT TARGETED CONJUGATES | Arbutus Biopharma Corporation (CA) | 2021-09-08 | — | — | EP | disclosed |
| EP-3873530-A1 | THERAPEUTIC METHODS | Genevant Sciences GmbH (CH) | 2021-09-08 | — | — | EP | disclosed |
| CN-113226332-A | Bivalent targeting conjugates | 阿布特斯生物制药公司 | 2021-08-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220062323-A1 | BIVALENT TARGETED CONJUGATES | ERBB2, PCNA, MRE11 | LMNA 1950/4885KMT2A 160/4885POLB 129/4885 |
| US-20220031847-A1 | THERAPEUTIC METHODS | NUP205, HNRNPH3, FUS | LMNA 64/4885KMT2A 2323/4885POLB 380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.