Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5972394 | 0.74 | MEN1 (0.40) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| SCHEMBL4511023 | 0.72 | HSD17B10 (0.42) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| SCHEMBL10639925 | 0.71 | HSD17B10 (0.44) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| SCHEMBL6019014 | 0.71 | HSD17B10 (0.44) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| SCHEMBL10639927 | 0.71 | HSD17B10 (0.44) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| Hydrochloric Acid SCHEMBL10639897 | 0.69 | HSD17B10 (0.43) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| Hydrochloric Acid SCHEMBL10636650 | 0.69 | HSD17B10 (0.43) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| SCHEMBL14851770 | 0.68 | KMT2A (0.40) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 | |
| SCHEMBL202165 | 0.68 | SLC22A6 (0.39) | POLBSMN1; SMN2TDP1CYP2C9CYP2C19 | |
| SCHEMBL1233845 | 0.67 | HSD17B10 (0.55) | HSD17B10POLBSMN1; SMN2TDP1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043319-A1 | ANTIBODY-DRUG COMPLEX | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2024-02-29 | — | — | WO | disclosed |
| EP-3873532-A1 | DC-SIGN ANTIBODY DRUG CONJUGATES | Novartis AG (CH) | 2021-09-08 | — | — | EP | disclosed |