SCHEMBL202165

SCHEMBL202165

CCOC(CC(=O)O)OCC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.39
ALOX15 P16050 1/20 0.39
FFAR3 O14843 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 2/20 0.36
THRB P10828 1/20 0.36
GPR84 Q9NQS5 4/20 0.35
PGD P52209 1/20 0.35
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
FFAR1 O14842 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26007106 0.89 GPR84 (0.34) SLC22A6ALOX15FFAR3LMNAGPR84
SCHEMBL30616013 0.85 ALOX15 (0.43) SLC22A6ALOX15SMN1; SMN2LMNATHRB
SCHEMBL16411803 0.81 LDHA (0.33) FFAR3THRBFFAR1
SCHEMBL9747219 0.80 TSHR (0.37) ALOX15THRBALDH1A1FFAR1
SCHEMBL2874716 0.79 ALDH1A1 (0.43) ALOX15TDP1LMNATHRBALDH1A1
SCHEMBL1878811 0.79 ALDH1A1 (0.43) ALOX15TDP1LMNATHRBALDH1A1
SCHEMBL3989533 0.78 FOLH1 (0.44) TDP1SMN1; SMN2THRB
SCHEMBL21081924 0.77 ALDH1A1 (0.40) FFAR3TDP1LMNATHRBALDH1A1
SCHEMBL22906066 0.77
SCHEMBL4483900 0.77 TDP1 (0.43) FFAR3TDP1LMNATHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114436809-B Method for preparing diethyl maleate by carrying out depolymerization on lignin under catalysis of iron oxide loaded by USY molecular sieve 华南理工大学 2023-01-06 CN claimed
CN-108997340-A Synthetic method of 5-bromo-7-azaindole 山东轩德医药科技有限公司 2018-12-14 CN claimed
EP-2482996-B1 METHOD FOR THE SPOT REPAIR OF SCRATCH-RESISTANT PAINT FILMS BASF COATINGS GMBH (DE) 2016-03-30 EP claimed
EP-1644384-B1 PROCESS AND INTERMEDIATES FOR THE SYNTHESIS OF ENTECAVIR BRISTOL MYERS SQUIBB CO (US) 2012-10-31 EP claimed
EP-1242382-B1 TRICYCLIC PROTEIN KINASE INHIBITORS WYETH CORP (US) 2007-02-07 EP claimed
EP-1140933-B1 PROCESS FOR PREPARING N6-SUBSTITUTED DEAZA-ADENOSINE DERIVATIVES AVENTIS PHARMA INC (US) 2004-09-08 EP claimed
EP-0662970-A1 PROCESS FOR THE PREPARATION OF 2-AMINO-6-CHLOROPURINE SMITHKLINE BEECHAM PLC (GB) 1995-07-19 EP claimed
EP-0319228-B1 Novel compounds BEECHAM GROUP PLC (GB) 1994-11-02 EP claimed
WO-1994007892-A1 PROCESS FOR THE PREPARATION OF 2-AMINO-6-CHLOROPURINE SMITHKLINE BEECHAM PLC (GB) 1994-04-14 WO claimed
US-12600705-B2 Heat shock protein modulators and anti-Huntington disease therapeutic agents UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2026-04-14 US disclosed
WO-2025124429-A1 AROMATIC AMINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京康辰药业股份有限公司 2025-06-19 WO disclosed
US-20240327388-A1 QUINOLINAMINE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN PHARMACEUTICALS JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2024-10-03 US disclosed
US-20240287063-A1 METHIONINE ADENOSYLTRANSFERASE 2A INHIBITOR NANJING CHIA TAI TIANQING PHARMACEUTICAL CO., LTD. (CN) 2024-08-29 US disclosed
CN-115703792-B Tricycle derivative and preparation method and medical application thereof 深圳信立泰药业股份有限公司 2024-08-13 CN disclosed
US-4269980-A TRANQUILIZERS; ANTICONVULSANTS AMERICAN CYANAMID COMPANY (US) 1981-05-26 US disclosed
US-4110116-A Fogged direct positive silver halide emulsion containing a cyanine dye having at least one benzoxazole or benzothiazole nucleus substituted with halogen atoms MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-29 US disclosed
US-4093812-A MICROBIOCIDES, DISINFECTANTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1978-06-06 US disclosed
US-4034093-A INHIBITION OF XANTHINEOXIDASE BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DT) 1977-07-05 US disclosed
US-4003750-A METHINE DYES EASTMAN KODAK COMPANY (US) 1977-01-18 US disclosed
US-3865824-A 2-Aryl-7-substituted pyrazolo {8 1,5{i a{b {9 1,3,5-triazines ICN PHARMACEUTICALS 1975-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287063-A1 METHIONINE ADENOSYLTRANSFERASE 2A INHIBITOR MAT2A, MAT2B, MAT1A SLC22A6 1003/4885ALOX15 3223/4885FFAR3 3782/4885
US-12600705-B2 Heat shock protein modulators and anti-Huntington disease therapeutic agents HEATR1, HSPH1, HEATR6 SLC22A6 2312/4885ALOX15 2750/4885FFAR3 2637/4885
US-20240327388-A1 QUINOLINAMINE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN PHARMACEUTICALS QARS1, THEM6, CYP4F11 SLC22A6 407/4885ALOX15 1335/4885FFAR3 2474/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.