SCHEMBL2377987

SCHEMBL2377987

C[C@H]1OC([O])[C@@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.42
CA9 Q16790 2/20 0.42
CA12 O43570 1/20 0.42
FUCA1 P04066 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.34
CA1 P00915 6/20 0.33
GBA1 P04062 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28145005 1.00 CA2 (0.42) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL209165 1.00 CA2 (0.42) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL3712080 1.00 CA2 (0.42) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL3712541 1.00 CA2 (0.42) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL2504504 1.00 CA2 (0.42) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL81581 1.00 CA2 (0.42) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL23541364 0.78 FUCA1 (0.48) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL12556709 0.78 FUCA1 (0.48) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL11962132 0.78 FUCA1 (0.48) CA2CA9CA12FUCA1SMN1; SMN2
SCHEMBL22923476 0.78 FUCA1 (0.48) CA2CA9CA12FUCA1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010102673-A1 HELLEBRIN AND HELLEBRIGENIN DERIVATIVES UNIBIOSCREEN S.A. (BE) 2010-09-16 WO claimed
WO-2009033505-A1 HELLEBRIN DERIVATIVES UNIBIOSCREEN S.A. (BE) 2009-03-19 WO claimed
US-20060252708-A1 Compositions of flavones and long chain fatty acid derivatives isolated from plants and methods related thereto for the control of prostate disorders SHENZHEN CHIPSCREEN BIOSCIENCES, LTD. (GN) 2006-11-09 US claimed
EP-0535595-B1 Manufacture and use of novel glycosides of catechol estrogens APPLIED BIOCHEMISTRY INST (JP) 1997-07-02 EP claimed
US-5405944-A Useful in the prevention and treatment of lipid peroxide- and free radical-related diseases INSTITUTE OF APPLIED BIOCHEMISTRY (JP) 1995-04-11 US claimed
EP-0535595-A2 Manufacture and use of novel glycosides of catechol estrogens Institute of Applied Biochemistry (JP) 1993-04-07 EP claimed
WO-2024042239-A1 GLYCOSYLATED PSILOCIN DERIVATIVES AND METHODS OF USE CY BIOPHARMA AG (CH) 2024-02-29 WO disclosed
US-11891360-B2 Glycosylated psilocybin derivatives and methods of using Enveric Biosciences Canada Inc. (CA) 2024-02-06 US disclosed
WO-2023217800-A2 GLYCOSYLATED COMPOSITIONS AND METHODS OF USE CY BIOPHARMA AG (CH) 2023-11-16 WO disclosed
WO-2023102659-A1 GLYCOSYLATED ISOPROPYLAMINE MESCALINE DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2023-06-15 WO disclosed
WO-2023102658-A1 GLYCOSYLATED MESCALINE DERIVATIVES AND METHODS OF USING Enveric Biosciences Canada Inc. (CA) 2023-06-15 WO disclosed
US-20230086396-A1 GLYCOSYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING MAGICMED INDUSTRIES INC. (CA) 2023-03-23 US disclosed
US-11564967-B1 Oral compositions containing extracts of a betel leaf and related methods Huynh, Tran Ky (VN) 2023-01-31 US disclosed
US-5739302-A SUBJECTING ACETOXYESTROGEN TO FRIES REARRANGEMENT IN PRESENCE OF ACETYL CHLORIDE, USING DAKIN REACTION TO REPLACE ACETYL GROUP WITH HYDROXYL GROUP AT ALKALINE PH INSTITUTE OF APPLIED BIOCHEMISTRY (JP) 1998-04-14 US disclosed
EP-0535595-B1 Manufacture and use of novel glycosides of catechol estrogens APPLIED BIOCHEMISTRY INST (JP) 1997-07-02 EP disclosed
EP-0688785-A2 Manufacture of catechol estrogens derivatives Institute of Applied Biochemistry (JP) 1995-12-27 EP disclosed
US-5405944-A Useful in the prevention and treatment of lipid peroxide- and free radical-related diseases INSTITUTE OF APPLIED BIOCHEMISTRY (JP) 1995-04-11 US disclosed
US-5405944-A Useful in the prevention and treatment of lipid peroxide- and free radical-related diseases INSTITUTE OF APPLIED BIOCHEMISTRY (JP) 1995-04-11 US disclosed
EP-0535595-A2 Manufacture and use of novel glycosides of catechol estrogens Institute of Applied Biochemistry (JP) 1993-04-07 EP disclosed
EP-0535595-A2 Manufacture and use of novel glycosides of catechol estrogens Institute of Applied Biochemistry (JP) 1993-04-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252708-A1 Compositions of flavones and long chain fatty acid derivatives isolated from plants and methods related thereto for the control of prostate disorders FASN, RFT1, FFAR1 CA2 3808/4885CA9 4039/4885CA12 4595/4885
US-20230086396-A1 GLYCOSYLATED PSILOCYBIN DERIVATIVES AND METHODS OF USING UGT8, UGT2B7, UGT1A9 CA2 4857/4885CA9 3774/4885CA12 3230/4885
US-11891360-B2 Glycosylated psilocybin derivatives and methods of using UGT8, UGT2B7, UGT1A9 CA2 4857/4885CA9 3774/4885CA12 3230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.