Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 7/20 | 0.59 |
| ▸ | MGAM | O43451 | 6/20 | 0.59 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.59 |
| ▸ | SI | P14410 | 6/20 | 0.59 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC9A1 | P19634 | 5/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535030 | 0.95 | ASAH1 (0.64) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL535094 | 0.94 | ASAH1 (0.66) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL5793440 | 0.94 | ASAH1 (0.66) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL534984 | 0.94 | ASAH1 (0.66) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL534899 | 0.94 | ASAH1 (0.66) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL18206302 | 0.94 | ASAH1 (0.66) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL535029 | 0.94 | ASAH1 (0.66) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL337266 | 0.94 | ASAH1 (0.66) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL535388 | 0.91 | KMT2A (0.59) | KMT2AHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL534954 | 0.87 | ASAH1 (0.58) | KMT2AHPGDHSD17B10MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11479579-B2 | Therapeutic compounds and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-10-25 | — | — | US | disclosed |
| US-11479579-B2 | Therapeutic compounds and methods | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2022-10-25 | — | — | US | disclosed |
| US-20210277055-A1 | THERAPEUTIC COMPOUNDS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-09-09 | — | — | US | disclosed |
| US-20210277055-A1 | THERAPEUTIC COMPOUNDS AND METHODS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2021-09-09 | — | — | US | disclosed |
| CN-101384674-B | Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation comprising said colored metallic pigment | TOYO ALUMINIUM KABUSHIKI KAISHA (JP) | 2011-12-28 | — | — | CN | disclosed |
| CN-101384674-A | Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation comprising said colored metallic pigment | TOYO ALUMINIUM KK (JP) | 2009-03-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11479579-B2 | Therapeutic compounds and methods | SNCA, PARK7, PSEN2 | KMT2A 4463/4885HPGD 1054/4885HSD17B10 1086/4885 |
| US-20210277055-A1 | THERAPEUTIC COMPOUNDS AND METHODS | SNCA, PARK7, PSEN2 | KMT2A 4463/4885HPGD 1054/4885HSD17B10 1086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.