Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255129 | 0.89 | HASPIN (0.33) | HASPIN | |
| SCHEMBL20207236 | 0.85 | HASPIN (0.34) | HASPIN | |
| SCHEMBL20207271 | 0.85 | HASPIN (0.34) | HASPIN | |
| SCHEMBL20037627 | 0.80 | HASPIN (0.36) | HASPIN | |
| SCHEMBL25228212 | 0.80 | HASPIN (0.36) | HASPIN | |
| SCHEMBL25271256 | 0.80 | HASPIN (0.36) | HASPIN | |
| SCHEMBL30461026 | 0.80 | HASPIN (0.36) | HASPIN | |
| SCHEMBL20207274 | 0.76 | PKM (0.39) | — | |
| SCHEMBL20037653 | 0.76 | PKM (0.39) | — | |
| SCHEMBL25225710 | 0.75 | HASPIN (0.36) | HASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11261182-B2 | Crystal of pyrido[3,4-d]pyrimidine derivative or solvate thereof | TEIJIN PHARMA LIMITED (JP) | 2022-03-01 | — | — | US | disclosed |
| US-20210276997-A1 | CRYSTAL OF PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE OR SOLVATE THEREOF | TEIJIN PHARMA LIMITED (JP) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261182-B2 | Crystal of pyrido[3,4-d]pyrimidine derivative or solvate thereof | CDK6, CDK4, CDKL4 | HASPIN 2031/4885 |
| US-20210276997-A1 | CRYSTAL OF PYRIDO[3,4-D]PYRIMIDINE DERIVATIVE OR SOLVATE THEREOF | CDK6, CDK4, CDKL4 | HASPIN 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.