Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009065 | 1.00 | SCN9A (0.35) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL21857662 | 0.91 | SCN9A (0.34) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL21953200 | 0.91 | SCN9A (0.34) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL30066002 | 0.91 | SCN9A (0.34) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL21857661 | 0.91 | SCN9A (0.34) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL19396321 | 0.90 | CA12 (0.36) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL15306196 | 0.90 | CA12 (0.36) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL29438019 | 0.90 | CA12 (0.36) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL31009068 | 0.87 | SCN9A (0.39) | SCN9ACTSSCTSKMAPTALDH1A1 | |
| SCHEMBL23750239 | 0.87 | SCN9A (0.39) | SCN9ACTSSCTSKMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210276985-A1 | NOVEL COMPOUNDS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-09-09 | — | — | US | disclosed |
| US-20210276985-A1 | NOVEL COMPOUNDS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210276985-A1 | NOVEL COMPOUNDS | NR3C2, AKR1C3, MC2R | SCN9A 2204/4885CTSS 3282/4885CTSK 4002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.