⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45233 | 0.62 | — | — | |
| SCHEMBL6244 | 0.62 | — | — | |
| SCHEMBL15547959 | 0.62 | TDP1 (0.31) | — | |
| SCHEMBL15547958 | 0.62 | TDP1 (0.31) | — | |
| SCHEMBL25219547 | 0.59 | — | — | |
| SCHEMBL2150133 | 0.59 | — | — | |
| SCHEMBL9117261 | 0.59 | — | — | |
| Ammonia Solution, Strong SCHEMBL22129991 | 0.59 | — | — | |
| SCHEMBL21268118 | 0.59 | — | — | |
| SCHEMBL156966 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 610 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210252154-A1 | MULTICOMPONENT DEGRADABLE CATIONIC POLYMERS | THE JOHNS HOPKINS UNIVERISTY | 2021-08-19 | — | — | US | claimed |
| US-20210220287-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | THE JOHNS HOPKINS UNIVERSITY | 2021-07-22 | — | — | US | claimed |
| US-20200330396-A1 | NONVIRAL GENE TRANSFER TO THE SUPRACHOROIDAL SPACE | THE JOHNS HOPKINS UNIVERSITY | 2020-10-22 | — | — | US | claimed |
| US-20200297851-A1 | MULTICOMPONENT DEGRADABLE CATIONIC POLYMERS | UNIV JOHNS HOPKINS (US) | 2020-09-24 | — | — | US | claimed |
| WO-2019070727-A2 | NONVIRAL GENE TRANSFER TO THE SUPRACHOROIDAL SPACE | THE JOHNS HOPKINS UNIVERSITY (US) | 2019-04-11 | — | — | WO | claimed |
| US-20180177881-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY | 2018-06-28 | — | — | US | claimed |
| EP-2923692-B1 | Beta-amino ester compounds and uses thereof | LIVING PROOF INC (US) | 2018-05-30 | — | — | EP | claimed |
| EP-1401918-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING BIODEGRADABLE POLY(BETA-AMINO ESTERS) | MASSACHUSETTS INST TECHNOLOGY (US) | 2018-03-07 | — | — | EP | claimed |
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-01 | — | — | US | claimed |
| US-20170258738-A1 | Multilayer Compositions, Coated Devices And Use Thereof | DEPARTMENT OF DEFENSE | 2017-09-14 | — | — | US | claimed |
| US-6207704-B1 | Type 2 methionine aminopeptidase [MetAP2] inhibitors and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2001-03-27 | — | — | US | claimed |
| WO-1998056372-A1 | TYPE 2 METHIONINE AMINOPEPTIDASE (MetAP2) INHIBITORS AND USES THEROF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-12-17 | — | — | WO | claimed |
| EP-0084046-B1 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1987-03-18 | — | — | EP | claimed |
| EP-0084046-A4 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN. | NAT PATENT DEV CORP (US) | 1984-01-12 | — | — | EP | claimed |
| EP-0084046-A1 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN. | NAT PATENT DEV CORP (US) | 1983-07-27 | — | — | EP | claimed |
| EP-0070897-A4 | Contact lenses made from modified synthetic hydrogels. | NAT PATENT DEV CORP (US) | 1983-06-17 | — | — | EP | claimed |
| US-4388428-A | DIMENSIONALLY STABLE HYDROGEL | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1983-06-14 | — | — | US | claimed |
| EP-0070897-A1 | Contact lenses made from modified synthetic hydrogels. | NAT PATENT DEV CORP (US) | 1983-02-09 | — | — | EP | claimed |
| WO-1983000339-A1 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN | NAT PATENT DEV CORP (US) | 1983-02-03 | — | — | WO | claimed |
| WO-1982002716-A1 | MODIFIED SYNTHETIC HYDROGELS | NAT PATENT DEV CORP (US) | 1982-08-19 | — | — | WO | claimed |