Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523017 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP2C9HIF1APDE10AALPI | |
| Hydrochloric Acid SCHEMBL6408746 | 0.98 | CYP1A2 (0.53) | CYP1A2CYP2C9HIF1APDE10AALPI | |
| SCHEMBL19462808 | 0.81 | CYP1A2 (0.42) | CYP1A2CYP2C9HIF1APDE10AALPI | |
| SCHEMBL29430134 | 0.79 | CYP1A2 (0.53) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL502039 | 0.79 | CYP1A2 (0.53) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL839033 | 0.79 | CYP1A2 (0.53) | CYP1A2ALPIPKMPTGS1XIAP | |
| SCHEMBL502040 | 0.79 | CYP1A2 (0.53) | CYP1A2ALPIPKMPTGS1XIAP | |
| Dl-Phenylalanine SCHEMBL28044913 | 0.79 | SLC7A5 (0.59) | CYP1A2CYP2C9HIF1AALPIPKM | |
| SCHEMBL4529374 | 0.76 | CYP1A2 (0.50) | CYP1A2CYP2C9HIF1APDE10AHSD17B10 | |
| SCHEMBL31614353 | 0.76 | TPH1 (0.62) | HIF1AALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026162-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | claimed |
| US-20230192765-A1 | PEPTIDES TARGETING SHP2 AND USES THEREOF | Università Degli Studi di Roma "Tor Vergata" (IT) | 2023-06-22 | — | — | US | disclosed |
| EP-4114849-A1 | PEPTIDES TARGETING SHP2 AND USES THEREOF | Universita' degli Studi di Roma " Tor Vergata" (IT) | 2023-01-11 | — | — | EP | disclosed |
| WO-2021176072-A1 | PEPTIDES TARGETING SHP2 AND USES THEREOF | Università Degli Studi di Roma "Tor Vergata" (IT) | 2021-09-10 | — | — | WO | disclosed |
| CN-105143245-B | Anti-scaling material | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2021-02-05 | — | — | CN | disclosed |
| CN-109563131-A | Chiral peptide | 卡诺有限责任公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-108026162-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | disclosed |