Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.33 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468064 | 0.90 | RECQL (0.37) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL1864604 | 0.88 | RECQL (0.34) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL739909 | 0.87 | KDM4E (0.37) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL472735 | 0.86 | PDE3B (0.38) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL1304095 | 0.86 | CA1 (0.33) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL3118273 | 0.86 | RECQL (0.33) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL3359275 | 0.86 | PDE3B (0.40) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL536510 | 0.86 | PDE3B (0.36) | PDE3BPDE3ACA1CA2RECQL | |
| SCHEMBL3123277 | 0.84 | HTT (0.43) | RECQLKDM4EMAPTPKM | |
| SCHEMBL23784652 | 0.84 | RECQL (0.34) | PDE3BPDE3ACA1CA2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063144-B1 | ANTIPARASITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-09-08 | — | — | EP | disclosed |