Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468064 | 0.92 | RECQL (0.37) | RECQLPKMKDM4EMAPTHTT | |
| SCHEMBL31191610 | 0.88 | RXRA (0.38) | KDM4EMAPTCA1CA2 | |
| SCHEMBL2015664 | 0.87 | RXRB (0.47) | RECQLCA1CA2 | |
| SCHEMBL24894946 | 0.87 | RECQL (0.34) | RECQLPKMKDM4EMAPTHTT | |
| SCHEMBL3362297 | 0.87 | PDE3B (0.34) | KDM4EMAPTPDE3BPDE3A | |
| SCHEMBL30821160 | 0.86 | GPR52 (0.40) | KDM4ECA1CA2 | |
| SCHEMBL19723134 | 0.85 | HTT (0.33) | RECQLPKMKDM4EMAPTHTT | |
| SCHEMBL16688172 | 0.85 | KDM4E (0.39) | KDM4EMAPTCA1CA2 | |
| SCHEMBL23784647 | 0.84 | PDE3B (0.44) | RECQLPKMKDM4EMAPTPDE3B | |
| SCHEMBL3359275 | 0.84 | PDE3B (0.40) | RECQLPKMKDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063144-B1 | ANTIPARASITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-09-08 | — | — | EP | disclosed |