Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168419 | 0.81 | CYP1A2 (0.37) | ALDH1A1LMNAMAPTCYP1A2CA1 | |
| SCHEMBL28168420 | 0.81 | CYP1A2 (0.37) | ALDH1A1LMNAMAPTCYP1A2CA1 | |
| SCHEMBL28274259 | 0.81 | CYP1A2 (0.37) | ALDH1A1LMNAMAPTCYP1A2CA1 | |
| SCHEMBL18021124 | 0.77 | — | — | |
| SCHEMBL20738739 | 0.77 | CA12 (0.52) | ALDH1A1MAPK1EPHX2LMNAEPHX1 | |
| SCHEMBL478665 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTCA1CA2 | |
| SCHEMBL4279033 | 0.77 | CA12 (0.52) | ALDH1A1MAPK1EPHX2LMNAEPHX1 | |
| SCHEMBL4309663 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTCA1CA2 | |
| SCHEMBL3606966 | 0.77 | CA12 (0.52) | ALDH1A1MAPK1EPHX2LMNAEPHX1 | |
| SCHEMBL12136815 | 0.77 | ALDH1A1 (0.61) | ALDH1A1LMNAMAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452461-B1 | PIPERIDINES AS MENIN INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2021-09-08 | — | — | EP | disclosed |