SCHEMBL23786200

SCHEMBL23786200

CCC(C)c1nc(Nc2ccc3c(c2)C(=O)NC3=O)nc(Nc2ccc3c(c2)C(=O)NC3=O)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.47
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GLA P06280 1/20 0.46
HPGD P15428 3/20 0.44
ABCB1 P08183 1/20 0.43
ABCC1 P33527 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
ALOX12 P18054 1/20 0.42
CHEK1 O14757 1/20 0.41
CASP3 P42574 2/20 0.40
KMT2A Q03164 7/20 0.39
MEN1 O00255 6/20 0.39
EGFR P00533 2/20 0.39
ATIC P31939 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24700568 0.87 KDM4E (0.50) POLBKDM4EALDH1A1GLAHPGD
SCHEMBL23139610 0.84 KDM4E (0.48) POLBKDM4EALDH1A1GLAHPGD
SCHEMBL17210585 0.76 KCNH3 (0.62) POLBKDM4EALDH1A1GLAHPGD
SCHEMBL27256156 0.76 KMT2A (0.48) KDM4EALDH1A1GLAHPGDABCB1
SCHEMBL21635742 0.74 PRKD3 (0.47) KDM4EALDH1A1GLAHPGDABCB1
SCHEMBL1320459 0.70 SYK (0.47) POLBALDH1A1ALOX12KMT2AMEN1
SCHEMBL12386903 0.70 POLB (0.54) POLBKDM4EALDH1A1GLAHPGD
SCHEMBL4081850 0.68 KDM4E (0.61) POLBKDM4EALDH1A1GLAHPGD
SCHEMBL6341593 0.68 KDM4E (0.58) POLBKDM4EALDH1A1GLAHPGD
SCHEMBL13256664 0.68 POLB (0.67) POLBKDM4EALDH1A1GLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed