SCHEMBL23786255

SCHEMBL23786255

CC(C)(C)Cc1ccc2[nH]c3ccccc3c(=O)c2c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
POLB P06746 2/20 0.58
KMT2A Q03164 2/20 0.58
NPC1 O15118 2/20 0.58
GAA P10253 3/20 0.55
HTT P42858 3/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
GLA P06280 2/20 0.55
LMNA P02545 1/20 0.55
HPGD P15428 1/20 0.55
ATM Q13315 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CASP6 P55212 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ABCG2 Q9UNQ0 1/20 0.54
CTSV O60911 3/20 0.49
CTSL P07711 3/20 0.49
P2RY12 Q9H244 2/20 0.48
IMPDH2 P12268 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23306821 0.91 KIF11 (0.55) MEN1POLBKMT2ANPC1GAA
SCHEMBL20713914 0.87 KIF11 (0.57) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL13484111 0.83 MEN1 (0.59) MEN1POLBKMT2ANPC1GAA
SCHEMBL861749 0.82 PARP1 (0.59) MEN1KMT2AKDM4EALDH1A1LMNA
SCHEMBL26171264 0.82 KDM4E (0.48) MEN1KMT2AKDM4EALDH1A1HPGD
SCHEMBL20713913 0.81 KIF11 (0.67) KDM4EALDH1A1KIF11
SCHEMBL14922493 0.80 KIF11 (0.66) MEN1POLBKMT2ANPC1GAA
SCHEMBL13484452 0.77 GAA (0.56) MEN1POLBKMT2ANPC1GAA
SCHEMBL12452887 0.77 GAA (0.56) MEN1POLBKMT2ANPC1GAA
SCHEMBL15133584 0.77 MEN1 (0.55) MEN1POLBKMT2ANPC1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210278761-A1 COLORING PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-09-09 US disclosed