Remogliflozin

Remogliflozin

SCHEMBL2378682

Cc1c(Cc2ccc(OC(C)C)cc2)c(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)nn1C(C)C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 1.00
SLC5A1 P13866 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Remogliflozin SCHEMBL2253397 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL18629779 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL17034639 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL18307653 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL3730054 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL16153590 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL18629778 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL16155105 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL17127189 1.00 SLC5A2 (1.00) SLC5A2SLC5A1
Remogliflozin SCHEMBL13258819 0.95 SLC5A2 (0.90) SLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110224413-A1 CHEMICAL PROCESS GLAXOSMITHKLINE LLC 2011-09-15 US disclosed
US-20100167989-A1 ISOPROPOXYPHENYLMETHYL INHIBITORS OF SGLT2 AUSPEX PHARMACEUTICALS, INC. (US) 2010-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100167989-A1 ISOPROPOXYPHENYLMETHYL INHIBITORS OF SGLT2 SLC5A2, SLC5A1, SLC2A4 SLC5A2 1/4885SLC5A1 2/4885
US-20110224413-A1 CHEMICAL PROCESS SLC5A2, SLC5A1, UGGT1 SLC5A2 1/4885SLC5A1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.